Diffuse Bio
Diffuse Bio is a generative-AI protein design company founded in 2022 and backed by Y Combinator (W23).
About
Diffuse Bio is a generative-AI protein design company founded in 2022 and backed by Y Combinator (W23). It pairs diffusion-model design software (DiffuseSandbox) with wet-lab screening (RamaX) for therapeutic proteins, vaccines and enzymes, and is expanding into generating verified biological reward signals at scale for AI models.
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This company
BusinessLatest roundTotal raisedDate- Diffuse Bio
Diffuse Bio is a generative-AI protein design company founded in 2022 and backed by Y Combinator (W23). It pairs diffusion-model design software (DiffuseSandbox) with wet-lab screening (RamaX) for therapeutic proteins, vaccines and enzymes, and is expanding into generating verified biological reward signals at scale for AI models.
$500K
$500K
United States
BusinessLatest roundTotal raisedDate- DeepSeq.AI
DeepSeq.AI, founded in 2019 and based in California, is an AI protein drug discovery company that combines high-throughput wet-lab assays with protein language models and generative AI to predict and optimize biologics properties (affinity, specificity, immunogenicity, PK, manufacturability) for large biopharma partners. It has DARPA and NSF funding, accelerator backing from Merck Digital Sciences Studio, StartX and SkyDeck, and investment from Illumina Ventures and Zaka VC.
$620K
$620K - Lagomics
Lagomics is an early-stage biotech pairing generative AI protein design with a cell-free, DNA-barcoded multiplex validation platform that tests thousands of AI-designed protein interactions in a single run. It runs women's-health therapeutic programs and supplies protein actives to cosmetics formulators; it is based at MBC BioLabs and supported by Activate, MIT Engine Blueprint and NVIDIA.
— - Terray Therapeutics
Combines AI with wet lab science to discover new small-molecule drugs
Undisclosed · $120M · 2024-10
$120M
China
BusinessLatest roundTotal raisedDate- 途深智合
AI protein design platform; conversational protein design platforms ProteinNova/ProteinEngine covering site-directed mutagenesis, enzyme engineering, de novo design, antibody structure and more
Angel · $1M · 2025-09
$1M - Matwings Technology
Protein design model MatwingsVenus with an automated lab platform, doing enzyme mining and directed evolution for universities and pharma companies
Series A · 2026-07
— - Levinthal Biotech
AI protein design services, with the proprietary all-atom protein design platform Pallatom
Series A · $14M · 2025-12
$14M
Europe
BusinessLatest roundTotal raisedDate- Isomorphic Labs
AI-driven drug design platform (IsoDDE engine): uses AlphaFold-based technology to predict protein structures and design new drug molecules; builds its own therapeutic pipeline and conducts joint R&D with large pharmaceutical companies
Series B · $2.7B · 2026-05
$2.7B - Basecamp Research
Trains the EDEN foundation model on proprietary biodiversity genomic data and uses AI to design proteins and in vivo cell therapies
Series C · $200M · 2026-09
$200M - Adaptyv Biosystems
AI protein design
Series A · 2026-09
—
Other / unspecified
BusinessLatest roundTotal raisedDate- Halmos Labs
AI-driven automated R&D systems for biotech and pharma that simulate experimental outcomes before wet-lab work and recommend the experiments that most reduce uncertainty
— - Galux
AI plus physics-based protein/antibody design platform (GaluxDesign) for drug discovery
Series B · $58M · 2026-02
$58M - 深度细胞
Combines AI with multiscale molecular physics to build a "virtual cell world model" for disease mechanism discovery and drug design
Seed · $14M · 2026-08
$14M
Confirmed rounds only. Matched on subsector, sector, stage and funding scale — each verifiable on the company profiles.
Investors that may fit
Andreessen Horowitz
24 Life Sciences deals in the last 24 months · 22 in Silicon Valley
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