Nutanix

Prime Intellect, founded in 2023 and headquartered in San Francisco, builds decentralized AI training infrastructure. The company offers a full-stack toolkit covering compute, reinforcement learning, and evaluation, enabling enterprises to train their own agentic systems without relying on frontier AI labs. Customers include Ramp and Zapier, with an annualized revenue run rate of approximately $100 million.

Loophole Labs (founded 2021, New York) builds virtualization infrastructure (Substrate hypervisor, Architect) for zero-downtime live migration and hibernate/wake of stateful Kubernetes workloads, plus AGX, a microVM sandbox platform for AI agents. Backed by Amplify Partners, Cervin Ventures and Peak XV; acquired by LiveKit on Sept 24, 2026.

Thunder Compute is a systems research lab building GPU virtualization software, founded in 2022 and headquartered in San Francisco, and a member of Y Combinator's Summer 2024 batch. Its core technology, GPU-over-TCP, abstracts GPUs as network resources rather than bare-metal allocations, running invisibly beneath workloads to improve scheduling and utilization across data centers and partner GPU fleets. The company positions itself as VMware for GPUs and operates its own on-demand GPU cloud (per-minute billing, one-click VSCode connection) as a production testbed alongside enterprise software partnerships.

Open-source AI compute orchestration platform unifying AI workloads across clouds, Kubernetes and GPU providers.

Infinity, founded in August 2025 by former Google Brain researcher and AGI House co-founder Jeremy Nixon, builds a universal inference software layer for heterogeneous AI chips. Its autonomous agent Ignition automatically generates, tests and optimizes the low-level compute kernels that determine how efficiently a chip runs AI models — positioned as a CUDA alternative — and already works with chipmakers such as d-Matrix with several million dollars in ARR.

DeepKernel (Beijing DeepKernel Technology Co., Ltd.), founded in April 2026 in Beijing, builds sovereign AI infrastructure across compute, learning and interaction layers, including a Trust Router, a trusted data-execution base and GPU confidential-computing environments for finance, healthcare, government and state-owned enterprises. Its R&D collaborates with a Tsinghua computer science group; team members come from Google, VMware, Broadcom, ByteDance and Alibaba.