Undecimal Bio

NeuShen Therapeutics, founded in 2022 by Dr. Joan Huaqiong Shen, is a clinical-stage international biotech company headquartered in Shanghai with an R&D center in Boston, dedicated to innovative therapies for psychiatric and neurological disorders through its NeuChime small-molecule discovery platform and NeuGem AAV gene therapy platform. Its pipeline includes NS-136 (an M4 positive allosteric modulator for schizophrenia and Alzheimer's-related agitation, in clinical trials in Australia) and NS-041 (a KCNQ2/3 activator for focal-onset seizures and major depressive disorder, IND accepted by China's CDE in December 2023).

Isomorphic Labs is a drug discovery company spun out of DeepMind and founded in 2022 in London, applying AI to drug discovery and design including protein structure prediction via AlphaFold.

Insilico Medicine, founded in 2019 in Shanghai, China, is a developer of drug candidates for anti-aging and cancer treatment.

Terray Therapeutics, founded in 2018 in Los Angeles, combines artificial intelligence with wet-lab science to discover novel small-molecule drugs.

Network Bio is a Palo Alto, California biotechnology company founded in 2022 that builds disease-specific AI models from human biological data. Its vertically integrated platform combines a biological research network that sources, links and structures tissue, blood and longitudinal clinical outcomes from leading U.S. academic medical centers (Mass General Brigham, University of Pennsylvania, Duke University, University of Colorado Anschutz and UCSF, spanning 500,000+ patients across oncology, immunology, metabolic and cardiovascular disease) into AI-ready datasets, with a bio-native AI architecture purpose-built to learn from multimodal biological data, overcome technical confounders and batch effects, and generate interpretable representations of disease biology that generalize across diseases, tissues and modalities.

Onepot, founded in 2023 in South San Francisco, USA, synthesizes small molecules for drug discovery using AI-driven automated synthesis for biopharmaceutical companies.