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📍 San Carlos · Silicon ValleyFounded 2025

About

Powerhouse Biology, Inc. is an early-stage biotech based in San Carlos, California, developing precision protein and peptide therapeutics targeting mitochondrial dysfunction, with applications in cell manufacturing yields, cell-therapy efficacy and late-onset diseases such as Parkinson's and Alzheimer's.

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Founders / team· 2

Mariëlle van KootenRachel Jacobson
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Powerhouse BiologyMariëlle van KootenMariëlle van KootenRachel JacobsonRachel Jacobson
CompanyInvestorFounders / teamCo-investment (thicker arc = more shared deals, ×N marks the count)Bigger circle = stronger signal (activity / coverage / interest) · ⛶ fullscreen · scroll / pinch to zoom · hover to highlight · drag nodes · click a node to open its profile

Comparable companies· by market

This company

  • Powerhouse Biology

    Powerhouse Biology, Inc. is an early-stage biotech based in San Carlos, California, developing precision protein and peptide therapeutics targeting mitochondrial dysfunction, with applications in cell manufacturing yields, cell-therapy efficacy and late-onset diseases such as Parkinson's and Alzheimer's.

Confirmed rounds only. Matched on subsector, sector, stage and funding scale — each verifiable on the company profiles.

Investors that may fit

General Catalyst

40 Life Sciences deals in the last 24 months · 36 in Silicon Valley

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Y Combinator

38 Life Sciences deals in the last 24 months · 31 in Silicon Valley

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Andreessen Horowitz

24 Life Sciences deals in the last 24 months · 22 in Silicon Valley

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Khosla Ventures

21 Life Sciences deals in the last 24 months · 20 in Silicon Valley

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Thrive Capital

18 Life Sciences deals in the last 24 months · 15 in Silicon Valley

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Lightspeed

17 Life Sciences deals in the last 24 months · 15 in Silicon Valley

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Ranked by each firm’s deals in this sector over the last 24 months, weighted by nearby stage and shared geography. Indicative only — no rating judgment.

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